Mechanical transduction by membrane ion channels: a mini review

Mol Cell Biochem. 1991 May 29-Jun 12;104(1-2):57-60. doi: 10.1007/BF00229804.


There are ion channels in the cell membrane that are sensitive to stress in the membrane cytoskeleton. Some channels turn on with stress, others turn off. In specialized receptors such as those involved in hearing, touch, etc. the role of the channels is clear. However, virtually all cells have these channels, and we don't yet know the physiological role of the channels although it is reasonable to suppose that they are involved in the control of cell size, either acutely as in volume regulation, or trophically as in the control of cell division.

Publication types

  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, Non-P.H.S.
  • Research Support, U.S. Gov't, P.H.S.
  • Review

MeSH terms

  • Animals
  • Humans
  • Ion Channels / metabolism*
  • Signal Transduction*
  • Stress, Mechanical


  • Ion Channels