Primary pulmonary hypertension: 3D dynamic perfusion MRI for quantitative analysis of regional pulmonary perfusion

AJR Am J Roentgenol. 2007 Jan;188(1):48-56. doi: 10.2214/AJR.05.0135.


Objective: The purpose of this study was to determine whether quantitative pulmonary perfusion parameters obtained from 3D dynamic contrast-enhanced MR perfusion data can be used to assess the severity of primary pulmonary hypertension (PPH) as indicated by pulmonary vascular resistance (PVR) and mean pulmonary artery pressure (MPAP).

Conclusion: Three-dimensional dynamic contrast-enhanced MRI has potential for assessment of disease severity as indicated by PVR and MPAP in patients with PPH.

Publication types

  • Comparative Study
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Aged
  • Algorithms
  • Blood Pressure*
  • Contrast Media
  • Female
  • Gadolinium DTPA*
  • Humans
  • Hypertension, Pulmonary / diagnosis*
  • Image Enhancement / methods*
  • Image Interpretation, Computer-Assisted / methods
  • Imaging, Three-Dimensional / methods*
  • Lung / blood supply
  • Lung / pathology
  • Magnetic Resonance Imaging / methods*
  • Male
  • Middle Aged
  • Perfusion
  • Pulmonary Circulation*
  • Reproducibility of Results
  • Sensitivity and Specificity
  • Severity of Illness Index


  • Contrast Media
  • Gadolinium DTPA