Friendly and dangerous signals: is the tissue in control?

Nat Immunol. 2007 Jan;8(1):11-3. doi: 10.1038/ni0107-11.


In their own defense, tissues send a panoply of signals that initiate immunity and guide the choice of effector class. T(H)1-T(H)2 and T(reg) is far too simple a representation of the breathtaking variety of the resulting responses.

MeSH terms

  • Animals
  • Humans
  • Immunity*
  • Immunoglobulins / biosynthesis*
  • Immunoglobulins / classification
  • Signal Transduction*
  • T-Lymphocytes, Helper-Inducer / classification*
  • T-Lymphocytes, Helper-Inducer / immunology*
  • Th1 Cells / immunology
  • Th2 Cells / immunology


  • Immunoglobulins