Photonic Boolean logic gates based on DNA aptamers

Chem Commun (Camb). 2007 Jan 14:(2):195-7. doi: 10.1039/b613201d. Epub 2006 Oct 24.

Abstract

We designed a pair of DNA-based logic gates that sense single-stranded DNAs and aptamer ligands to produce fluorescence outputs according to Boolean logic functions AND and OR.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adenosine / chemistry
  • Aptamers, Nucleotide / chemistry*
  • Base Sequence
  • Biosensing Techniques / methods
  • Computers, Molecular*
  • DNA, Single-Stranded / chemistry
  • Fluorescein / chemistry
  • Nucleic Acid Conformation
  • Polydeoxyribonucleotides / chemistry
  • Spectrometry, Fluorescence
  • Thrombin / chemistry

Substances

  • Aptamers, Nucleotide
  • DNA, Single-Stranded
  • Polydeoxyribonucleotides
  • Thrombin
  • Adenosine
  • Fluorescein