Curr Opin Cell Biol. 1991 Oct;3(5):792-9. doi: 10.1016/0955-0674(91)90052-z.


The thrombospondins are a family of proteins generated by alternative splicing and gene duplication, which contain binding sites for many soluble proteins and up to five cellular receptors. This family of modular proteins functions in regulation of cellular migration and proliferation as manifested in development, wound healing, angiogenesis and tumorigenesis.

Publication types

  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, P.H.S.
  • Review

MeSH terms

  • Amino Acid Sequence
  • Animals
  • Blood Platelets / chemistry
  • Blood Platelets / physiology*
  • CD36 Antigens
  • Humans
  • Molecular Sequence Data
  • Platelet Membrane Glycoproteins / chemistry
  • Platelet Membrane Glycoproteins / physiology*
  • Receptors, Cytoadhesin / physiology
  • Structure-Activity Relationship
  • Thrombospondins


  • CD36 Antigens
  • Platelet Membrane Glycoproteins
  • Receptors, Cytoadhesin
  • Thrombospondins