Castleman's disease, intermediate type: a case report

Indian J Pathol Microbiol. 2006 Oct;49(4):603-4.


Castleman's disease or giant lymph node hyperplasia is a distinct form of lymph node hyperplasia. Histologically, there are 2 variants, hyaline vascular variant which occurs in 90% of the cases and plasma cell type which is rare. We encountered a 70 year old man with Castleman's disease showing intermediate features consisting of both hyaline vascular and plasma cell elements presenting as cervical lymphadenopathy. Following surgical excision, the patient was relieved of his constitutional symptoms and had no recurrence even after 6 months of follow-up.

Publication types

  • Case Reports

MeSH terms

  • Aged
  • Castleman Disease / diagnosis
  • Castleman Disease / pathology*
  • Humans
  • Hyalin / metabolism*
  • Lymph Nodes / pathology*
  • Lymphatic Diseases / diagnosis
  • Lymphatic Diseases / pathology*
  • Male
  • Plasma Cells / cytology*