TOR regulation: sorting out the answers

Cell Metab. 2007 Jan;5(1):3-5. doi: 10.1016/j.cmet.2006.12.008.

Abstract

Components involved in vesicle trafficking processes such as secretion, endocytosis, and autophagy are gaining recognition as important regulators and effectors of target of rapamycin (TOR) signaling. A recent report by now implicates Pmr1, a secretory pathway Ca(2+)/Mn(2+) ATPase located in the Golgi apparatus, as a novel regulator of TOR and its downstream targets in yeast.

MeSH terms

  • Animals
  • Calcium-Transporting ATPases / genetics
  • Calcium-Transporting ATPases / metabolism*
  • Golgi Apparatus / metabolism
  • Humans
  • Models, Biological
  • Molecular Chaperones / metabolism*
  • Pemphigus, Benign Familial / metabolism
  • Phosphatidylinositol 3-Kinases / metabolism
  • Protein-Serine-Threonine Kinases
  • Saccharomyces cerevisiae / metabolism*
  • Saccharomyces cerevisiae Proteins / metabolism*
  • Signal Transduction*
  • Transport Vesicles / metabolism

Substances

  • Molecular Chaperones
  • SSC1 protein, S cerevisiae
  • Saccharomyces cerevisiae Proteins
  • Protein-Serine-Threonine Kinases
  • target of rapamycin protein, S cerevisiae
  • ATP2C1 protein, human
  • Calcium-Transporting ATPases