Fibrous papule of the nose with granular cells: two cases

J Cutan Pathol. 1991 Aug;18(4):284-7. doi: 10.1111/j.1600-0560.1991.tb01237.x.

Abstract

Two cases of fibrous papule of the nose (FPN) with granular cell features are presented and discussed. Both lesions have classic architectural features of FPN; however, the main stromal cells show large cytoplasmic granules of the type seen in granular cells. We are uncertain of the significance of these findings. Our hypotheses include a perifollicular granular cell reaction and a granular degenerative change of local dermal dendrocytes.

Publication types

  • Case Reports

MeSH terms

  • Granular Cell Tumor / diagnosis
  • Granular Cell Tumor / pathology*
  • Granular Cell Tumor / ultrastructure
  • Histocytochemistry
  • Humans
  • Male
  • Microscopy, Electron
  • Middle Aged
  • Nose Neoplasms / diagnosis
  • Nose Neoplasms / pathology*
  • Nose Neoplasms / ultrastructure
  • Skin Neoplasms / diagnosis
  • Skin Neoplasms / pathology*
  • Skin Neoplasms / ultrastructure
  • Staining and Labeling