Optical coherence tomography and focal electroretinogram evaluation of cystoid macular edema secondary to retinitis pigmentosa treated with intravitreal triamcinolone: case report

Eur J Ophthalmol. Nov-Dec 2006;16(6):883-6. doi: 10.1177/112067210601600620.

Abstract

Purpose: To assess macular structure and function by optical coherence tomography (OCT) and focal electroretinogram (FERG) before and after intravitreal triamcinolone acetonide (IVTA) administration for cystoid macular edema (CME) in a patient with retinitis pigmentosa (RP).

Methods: A 33-year-old man with RP and refractory bilateral macular edema was treated with IVTA in his left eye and evaluated with visual acuity, OCT, and FERG for 6 months. RESULTS. Compared to the fellow eye, after IVTA mean retinal thickness significantly decreased, while FERG amplitude and phase did not show significant changes at the end of follow-up. Visual acuity showed a significant tendency to improve.

Conclusions: In this case report, IVTA improved macular anatomy and visual acuity; this result, however, was not associated with a similar electrophysiologic response.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Electroretinography*
  • Fluorescein Angiography
  • Glucocorticoids / therapeutic use*
  • Humans
  • Injections
  • Macular Edema / diagnosis
  • Macular Edema / drug therapy*
  • Macular Edema / etiology
  • Male
  • Retina / drug effects*
  • Retina / pathology
  • Retinitis Pigmentosa / complications*
  • Tomography, Optical Coherence*
  • Triamcinolone Acetonide / therapeutic use*
  • Visual Acuity / drug effects
  • Vitreous Body

Substances

  • Glucocorticoids
  • Triamcinolone Acetonide