Two novel trimeric resveratrol derivatives from Cotylelobium lanceolatum

Chem Biodivers. 2005 Sep;2(9):1200-16. doi: 10.1002/cbdv.200590091.

Abstract

Two new resveratrol (= 5-[(E)-2-(4-hydroxyphenyl)ethenyl]benzene-1,3-diol) trimers, cotylelophenols A (1) and B (2), were isolated from the stem of Cotylelobium lanceolatum (Dipterocarpaceae), together with ten known resveratrol oligomers (3-12). The structures of the isolates were established on the basis of spectroscopic analyses, including a detailed NMR spectroscopic investigation of 1 under different conditions. Compound 1 is the first resveratrol trimer with a rearranged 4-hydroxyphenyl group. Four possible biogenetic pathways towards resveratrol oligomers are proposed (Scheme).

MeSH terms

  • Ericales / chemistry*
  • Molecular Structure
  • Resveratrol
  • Stilbenes / chemistry*

Substances

  • Stilbenes
  • Resveratrol