[Autochthonous hepatitis E in France]

Bull Acad Natl Med. 2006 Apr-May;190(4-5):973-80.
[Article in French]


Hepatitis E must no longer be considered simply as an exotic disease occasionally imported from developing countries. Autochthonous hepatitis E exists in France. In spite of certain difficulties and limits, biological markers of hepatitis E have to be included in algorithms for etiological diagnosis of acute hepatitis, even if the patient has not recently traveled abroad. Based on a recombinant protein of the viral capsid, more sensitive serological assays should soon be available. The potential severity of hepatitis E, especially during pregnancy, calls for a national surveillance program, including evaluation of the animal reservoir and the risk associated with drinking water and food.

Publication types

  • English Abstract

MeSH terms

  • Adult
  • Algorithms
  • Animals
  • Disease Reservoirs
  • Enzyme-Linked Immunosorbent Assay
  • Female
  • France / epidemiology
  • Genotype
  • Hepatitis Antibodies / analysis
  • Hepatitis E / diagnosis
  • Hepatitis E / epidemiology*
  • Hepatitis E / prevention & control
  • Hepatitis E / virology
  • Hepatitis E virus / genetics
  • Hepatitis E virus / immunology
  • Humans
  • Male
  • Polymerase Chain Reaction
  • Pregnancy
  • Pregnancy Complications, Infectious / diagnosis
  • Prevalence
  • RNA, Viral / analysis
  • Reverse Transcriptase Polymerase Chain Reaction
  • Risk Factors
  • Zoonoses


  • Hepatitis Antibodies
  • RNA, Viral