[OCT and PVEP examination in eyes with visible idiopathic optic disc drusen]

Klin Monbl Augenheilkd. 2006 Dec;223(12):993-6. doi: 10.1055/s-2006-927155.
[Article in German]


Objectives: It has been reported that the presence of optic disc drusen is mostly not associated with a reduction in function of the visual organ. At present by using more precise diagnostic tools it is possible to find more pathology. The aim of the study was to evaluate changes in peripapillar RNFL thickness and VEP parameters in a group of patients at the Department of Ophthalmology in Poznań, with diagnosed visible idiopathic optic disc drusen.

Materials and methods: We have reviewed the medical records of 7 patients (5 women and 2 men) age range 43 - 61 years, mean age 51 years, with idiopathic visible optic disc drusen confirmed by ultrasound B scan. RNFL were measured with use of an OCT system (Stratus, Zeiss): fast RNFL thickness = 3.4. VEP were evaluated with use of a 60 pattern.

Results: In all patients OCT has shown a thinnig of peripapillar retinal nerve fiber layer. The lowest values were found in the superior and inferior quadrants. In 9 eyes we recorded VEPs with prolonged latency P100 from 117.2 - 135.8 msec, with a small reduction of the P100 amplitude.

Conclusions: Idiopathic visible optic disc drusen are associated with changes in peripapillar RNFL thickness, especially in the superior and inferior quadrants. The anatomic pathology is related to functional abnormalities as confirmed with VEP. Detection of this type of drusen should be an indication to search for possible RNFL and VEP pathologies and to monitor their possible progression.

Publication types

  • English Abstract

MeSH terms

  • Adult
  • Evoked Potentials, Visual / physiology*
  • Female
  • Humans
  • Male
  • Middle Aged
  • Nerve Fibers / pathology
  • Nerve Fibers / physiology
  • Ophthalmoscopy
  • Optic Disk Drusen / diagnosis*
  • Optic Disk Drusen / physiopathology
  • Reaction Time / physiology
  • Reference Values
  • Retina / pathology
  • Retina / physiopathology
  • Tomography, Optical Coherence*
  • Ultrasonography
  • Visual Pathways / physiopathology