Adrenaline-induced digital ischaemia reversed with phentolamine

ANZ J Surg. 2006 Dec;76(12):1125-6. doi: 10.1111/j.1445-2197.2006.03954.x.

Abstract

Adrenaline autoinjectors are widely prescribed for self-treatment of anaphylactic syndromes. Accidental misfire into digits can cause prolonged significant ischaemia with serious outcomes. Phentolamine is a readily available treatment, which is easily and safely given in the emergency setting.

Publication types

  • Case Reports

MeSH terms

  • Adrenergic alpha-Agonists / administration & dosage
  • Adrenergic alpha-Agonists / adverse effects*
  • Adrenergic alpha-Antagonists / therapeutic use*
  • Adult
  • Autonomic Nerve Block
  • Epinephrine / administration & dosage
  • Epinephrine / adverse effects*
  • Fingers / blood supply*
  • Humans
  • Injections
  • Ischemia / chemically induced
  • Ischemia / drug therapy*
  • Male
  • Phentolamine / therapeutic use*

Substances

  • Adrenergic alpha-Agonists
  • Adrenergic alpha-Antagonists
  • Epinephrine
  • Phentolamine