A color version of the Hinsberg test: 1 degrees -3 degrees amine indicator

Chemistry. 2007;13(11):3082-8. doi: 10.1002/chem.200600905.


The Hinsberg test to recognize the type of amine (1 degrees -3 degrees amines), which has been established for more than 100 years and well documented in textbooks, is not possible without conducting complicated organic reactions. We report for the first time unique chemosensors that are capable of showing selective color changes toward 1 degrees -3 degrees amines as a color version of the Hinsberg test. This simple and straightforward qualitative analysis, using the synthesized novel compounds herein, can be considered a new innovative tool for discriminating 1 degrees -3 degrees amines as an alternative to the historical Hinsberg test.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Amines / chemistry*
  • Azo Compounds / chemical synthesis*
  • Biosensing Techniques*
  • Color*
  • Coloring Agents / chemical synthesis*
  • Crystallography, X-Ray
  • Hydrogen Bonding
  • Indicators and Reagents / chemistry*
  • Magnetic Resonance Spectroscopy


  • Amines
  • Azo Compounds
  • Coloring Agents
  • Indicators and Reagents