Histopathological mimicry in mucosal prolapse

Histopathology. 2007 Jan;50(1):97-102. doi: 10.1111/j.1365-2559.2006.02552.x.


Mucosal prolapse solitary rectal ulcer syndrome is a condition which has frequently confused both pathologists and surgeons alike. Despite its recognition in the nineteenth century, it continues to be a diagnostic challenge. The significance of correctly diagnosing this condition is that it avoids the morbidity and mortality associated with major surgery or the side-effects of long-term medical treatment. This review considers the histological features of mucosal prolapse and how it may mimic other pathological conditions.

Publication types

  • Review

MeSH terms

  • Diagnosis, Differential
  • Humans
  • Intestinal Mucosa / pathology*
  • Rectal Prolapse / complications
  • Rectal Prolapse / pathology*
  • Rectum / pathology*
  • Syndrome
  • Ulcer / complications
  • Ulcer / pathology*