Effectiveness of loaded sit-to-stand resistance exercise for children with mild spastic diplegia: a randomized clinical trial

Arch Phys Med Rehabil. 2007 Jan;88(1):25-31. doi: 10.1016/j.apmr.2006.10.006.


Objective: To investigate effectiveness of a functional strengthening program, the loaded sit-to-stand (STS) resistance exercise, for children with cerebral palsy (CP).

Design: A single-blind, randomized block design.

Setting: STS exercises were carried out at the children's homes.

Participants: Twenty children (12 boys, 8 girls; age range, 5-12y) with spastic diplegia CP and classified by the Gross Motor Function Classification System as level I or II were stratified by their severity and age and randomly allocated into either the experimental or control group.

Intervention: Both groups received their regular physical therapy. The experimental group underwent loaded STS exercise 3 times a week for 6 weeks.

Main outcome measures: Goal dimension scores of the Gross Motor Function Measure (GMFM), gait speed, 1 repetition maximum (1-RM) of the loaded STS, isometric strength of knee extensor, and Physiological Cost Index (PCI). The outcome measures were conducted at the beginning and end of the 6-week study.

Results: After loaded STS exercise, the experimental group showed statistically significant differences in GMFM goal dimension scores, 1-RM STS, and PCI from the control group. The changes in gait speed and isometric strength of the knee extensor did not differ significantly between the 2 groups.

Conclusions: After the loaded STS exercise, children with mild spastic diplegia improved their basic motor abilities, functional muscle strength, and walking efficiency.

Publication types

  • Multicenter Study
  • Randomized Controlled Trial
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Activities of Daily Living
  • Cerebral Palsy / classification
  • Cerebral Palsy / physiopathology*
  • Cerebral Palsy / rehabilitation*
  • Child
  • Child, Preschool
  • Energy Metabolism
  • Exercise Therapy / methods*
  • Female
  • Gait
  • Home Care Services
  • Humans
  • Isometric Contraction
  • Knee / physiopathology
  • Male
  • Muscle Strength
  • Muscle Strength Dynamometer
  • Psychomotor Performance
  • Severity of Illness Index
  • Single-Blind Method
  • Taiwan
  • Treatment Outcome
  • Weight Lifting*
  • Weight-Bearing