Evidence for PDGFRA, PDGFRB and KIT deregulation in an NSCLC patient

Br J Cancer. 2007 Jan 15;96(1):180-1. doi: 10.1038/sj.bjc.6603542.
No abstract available

Publication types

  • Case Reports
  • Comment
  • Letter
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Benzamides
  • Carcinoma, Non-Small-Cell Lung / diagnosis
  • Carcinoma, Non-Small-Cell Lung / drug therapy
  • Carcinoma, Non-Small-Cell Lung / metabolism*
  • Chemotherapy, Adjuvant
  • Chordoma / drug therapy
  • Chordoma / metabolism*
  • Chordoma / pathology
  • Disease Progression
  • Humans
  • Imatinib Mesylate
  • In Situ Hybridization, Fluorescence / methods
  • Lung Neoplasms / diagnosis
  • Lung Neoplasms / drug therapy
  • Lung Neoplasms / metabolism*
  • Male
  • Middle Aged
  • Neoplasm Recurrence, Local / drug therapy
  • Neoplasm Recurrence, Local / metabolism
  • Neoplasms, Second Primary / diagnosis
  • Neoplasms, Second Primary / drug therapy
  • Neoplasms, Second Primary / metabolism*
  • Piperazines / pharmacology
  • Piperazines / therapeutic use
  • Proto-Oncogene Proteins c-kit / drug effects
  • Proto-Oncogene Proteins c-kit / genetics
  • Proto-Oncogene Proteins c-kit / metabolism*
  • Pyrimidines / pharmacology
  • Pyrimidines / therapeutic use
  • Receptor, Platelet-Derived Growth Factor alpha / drug effects
  • Receptor, Platelet-Derived Growth Factor alpha / genetics
  • Receptor, Platelet-Derived Growth Factor alpha / metabolism*
  • Receptor, Platelet-Derived Growth Factor beta / drug effects
  • Receptor, Platelet-Derived Growth Factor beta / genetics
  • Receptor, Platelet-Derived Growth Factor beta / metabolism*
  • Sensitivity and Specificity

Substances

  • Benzamides
  • Piperazines
  • Pyrimidines
  • Imatinib Mesylate
  • Proto-Oncogene Proteins c-kit
  • Receptor, Platelet-Derived Growth Factor alpha
  • Receptor, Platelet-Derived Growth Factor beta