Reduction of adipose tissue and body weight: effect of water soluble calcium hydroxycitrate in Garcinia atroviridis on the short term treatment of obese women in Thailand

Asia Pac J Clin Nutr. 2007;16(1):25-9.


Fifty obese women with a body mass index (BMI) over 25 kg/m(2) were randomly allocated into two groups, 25 in each. Group 1, with a mean (+/-SEM) age of 40.0+/-2 years, received water soluble calcium hydroxycitrate (HCA) as Garcinia atroviridis. Group 2, with a mean age of 35.6+/-1.8 years, received placebo. All subjects were recommended a similar diet with 1000 Kcal/day. The trial lasted for 2 months. At baseline the means BMI of Group 1 and Group 2 were 27.5+/-0.2 kg/m(2) and 26.7+/-0.5 kg/m(2), respectively. Group 1 lost significantly more weight (2.8 vs. 1.4 kg, p<0.05) and at a greater rate than Group 2 throughout the study. The decrease in their body weight was due to a loss of fat storage as evidenced by a significant decrease in the triceps skin fold thickness. On a short-term basis, HCA in Garcinia atroviridis was an effective for weight management.

Publication types

  • Randomized Controlled Trial

MeSH terms

  • Adipose Tissue / drug effects
  • Adipose Tissue / metabolism*
  • Adolescent
  • Adult
  • Aged
  • Body Weight / physiology
  • Calcium Citrate / adverse effects
  • Calcium Citrate / therapeutic use*
  • Combined Modality Therapy
  • Consumer Product Safety
  • Diet, Reducing
  • Female
  • Garcinia / chemistry*
  • Humans
  • Middle Aged
  • Obesity / diet therapy
  • Obesity / drug therapy
  • Obesity / therapy*
  • Phytotherapy*
  • Plant Extracts / adverse effects
  • Plant Extracts / therapeutic use*
  • Treatment Outcome
  • Weight Loss / drug effects
  • Weight Loss / physiology


  • Plant Extracts
  • Calcium Citrate