Diffuse cutaneous leishmaniasis in an HIV-positive patient in western Africa

Australas J Dermatol. 2007 Feb;48(1):32-4. doi: 10.1111/j.1440-0960.2007.00323.x.

Abstract

A 36-year-old HIV1-positive woman presented with a 6-month history of a progressive papular and nodular eruption of the face and subsequent extensive spread to the rest of the skin. The diagnosis of diffuse cutaneous leishmaniasis was established by direct examination and skin biopsy. This atypical form had a dramatic improvement after a 21-day treatment with meglumine antimoniate. This clinical form may be confused with other endemic diseases in western Africa, especially leprosy.

MeSH terms

  • Africa, Western
  • Antiprotozoal Agents / administration & dosage
  • Antiprotozoal Agents / therapeutic use
  • Diagnosis, Differential
  • Facial Dermatoses / diagnosis*
  • Facial Dermatoses / drug therapy
  • Facial Dermatoses / pathology
  • Female
  • HIV Infections*
  • Humans
  • Injections, Intramuscular
  • Leishmaniasis, Diffuse Cutaneous / diagnosis*
  • Leishmaniasis, Diffuse Cutaneous / drug therapy
  • Leishmaniasis, Diffuse Cutaneous / pathology
  • Meglumine / administration & dosage
  • Meglumine / therapeutic use
  • Meglumine Antimoniate
  • Middle Aged
  • Organometallic Compounds / administration & dosage
  • Organometallic Compounds / therapeutic use

Substances

  • Antiprotozoal Agents
  • Organometallic Compounds
  • Meglumine
  • Meglumine Antimoniate