Altered left ventricular diastolic filling following a marathon is a reproducible phenomenon

Int J Cardiol. 2007 Oct 31;122(1):87-9. doi: 10.1016/j.ijcard.2006.11.042. Epub 2007 Jan 11.


The present study examined the reproducibility of alterations in left ventricular function and cardiac biomarkers in a cohort of athletes following two marathons, one year apart. Eight participants in the 2004 and 2005 London Marathons were tested pre- and post-race via echocardiography and humoral analysis. Reductions in diastolic filling, unrelated to loading or heart rate, following both marathons were reproducible within individuals, which may be a function of exercise duration. In contrast, exercise-induced cardiac troponin release was inconsistent.

Publication types

  • Letter

MeSH terms

  • Adult
  • Cohort Studies
  • Humans
  • Reproducibility of Results
  • Running / physiology*
  • Stroke Volume / physiology*
  • Ventricular Function, Left / physiology*