Traffic injuries are the leading cause of morbidity and mortality of children around the world. Economic development and quality of life are main components of public health. Using canonical correlation analysis, this study examined the relationship between quality of life and traffic fatality among children. Data were collected from 19 countries by using World Health Organization and OECD statistics. The results indicated that there is a strong relationship between quality of life and children traffic fatality. Growing quality of life has become protective against child traffic accident mortality. Increasing in gross national income per capita, life expectancy at birth number of years, road motor vehicles per thousand population, and share of persons of working age (15-64 years) in employment also increases children traffic safety.