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Review
, 61 (1), 105-18

Non-nucleoside Reverse Transcriptase Inhibitors: A Review

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Review

Non-nucleoside Reverse Transcriptase Inhibitors: A Review

L Waters et al. Int J Clin Pract.

Abstract

Non-nucleoside reverse transcriptase inhibitors form the backbone of antiretroviral treatment for many HIV-infected individuals. The tolerability, pill burden and efficacy associated with this class of agents make them a frequent choice for first-line therapy. Here we review nevirapine and efavirenz in terms of efficacy, resistance and toxicity, focusing particularly on the use of nevirapine to prevent mother-to-child transmission in developing countries.

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