Pertussis in Argentina and France

Vaccine. 2007 May 30;25(22):4335-9. doi: 10.1016/j.vaccine.2006.08.024. Epub 2006 Aug 31.


We have studied the epidemiology of pertussis in two countries, Argentina and France, which have similar histories of long-term mass vaccination with a whole-cell vaccine. Both countries display a comparable epidemiology, with an increase of the incidence of the disease in non-vaccinated newborns. We used pulsed-field gel electrophoresis (PFGE) analysis and genotyping to compare Bordetella pertussis clinical isolates recovered in Argentina and France in 2001-2004. The majority of the isolates harbors prn2 allele and belongs to PFGE IVbeta group. Isolates were found to be very similar genetically suggesting a common evolution of the disease in these two countries using the same vaccine.

Publication types

  • Letter
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Argentina / epidemiology
  • Bacterial Typing Techniques
  • Bordetella pertussis / classification*
  • Bordetella pertussis / genetics*
  • Bordetella pertussis / isolation & purification
  • Electrophoresis, Gel, Pulsed-Field
  • Evolution, Molecular
  • Female
  • France / epidemiology
  • Genotype
  • Humans
  • Immunization Schedule
  • Infant
  • Infant, Newborn
  • Male
  • Pertussis Vaccine / administration & dosage*
  • Vaccination
  • Whooping Cough / epidemiology*
  • Whooping Cough / microbiology
  • Whooping Cough / prevention & control*


  • Pertussis Vaccine