Pattern of subclinical pulmonary dysfunctions in Parkinson's disease and the effect of levodopa

Mov Disord. 2007 Feb 15;22(3):420-4. doi: 10.1002/mds.21330.


We performed a detailed evaluation of pulmonary function in 53 patients with idiopathic Parkinson's disease (PD) who did not have symptoms of pulmonary or cardiac dysfunction. There was a significant pulmonary dysfunction of restrictive type which partially responded to levodopa. Compared to men, women were more severely affected. Pulmonary function assessment is recommended in PD, irrespective of severity of disease.

Publication types

  • Comparative Study
  • Evaluation Study

MeSH terms

  • Adult
  • Antiparkinson Agents / therapeutic use*
  • Female
  • Humans
  • Levodopa / therapeutic use*
  • Lung Diseases / drug therapy*
  • Lung Diseases / etiology
  • Male
  • Middle Aged
  • Parkinson Disease / complications
  • Parkinson Disease / drug therapy*
  • Respiratory Function Tests / methods
  • Severity of Illness Index


  • Antiparkinson Agents
  • Levodopa