Porcine Enteric Caliciviruses: Genetic and Antigenic Relatedness to Human Caliciviruses, Diagnosis and Epidemiology

Vaccine. 2007 Jul 26;25(30):5453-66. doi: 10.1016/j.vaccine.2006.12.032. Epub 2006 Dec 29.

Abstract

Porcine enteric caliciviruses include sapoviruses and noroviruses. Porcine sapoviruses infect pigs of all ages and cause diarrhea in young pigs, whereas porcine noroviruses were detected exclusively from adult pigs without clinical signs. Importantly, certain porcine norovirus strains were genetically and antigenically related to human noroviruses. This raises public health concerns that pigs may be reservoirs for emergence of epidemic human norovirus strains. This article reviews the discovery of porcine noroviruses and sapoviruses, their classification, diagnosis, epidemiology and genetic and antigenic relatedness to human caliciviruses.

Publication types

  • Research Support, N.I.H., Extramural
  • Research Support, U.S. Gov't, Non-P.H.S.
  • Review

MeSH terms

  • Animals
  • Antibodies, Viral / immunology
  • Caliciviridae / classification*
  • Caliciviridae / genetics
  • Caliciviridae / immunology
  • Caliciviridae Infections / diagnosis
  • Caliciviridae Infections / epidemiology
  • Caliciviridae Infections / veterinary*
  • Caliciviridae Infections / virology*
  • Cross Reactions
  • Enteritis / diagnosis
  • Enteritis / epidemiology
  • Enteritis / veterinary*
  • Enteritis / virology*
  • Humans
  • Phylogeny
  • Swine Diseases / diagnosis
  • Swine Diseases / epidemiology
  • Swine Diseases / virology*

Substances

  • Antibodies, Viral