[Electrochemotherapy, a new antitumor treatment: first clinical trial]

C R Acad Sci III. 1991;313(13):613-8.
[Article in French]

Abstract

Electrochemotherapy (ECT) is a new antitumor treatment which consists in delivering electric pulses to the tumor some minutes after an intravenous injection of bleomycin. We report here the first clinical trial of ECT, applied to patients with permeation nodules of head and neck squamous carcinomas. ECT was well tolerated by patients, no serious incident occurred and a clear antitumor efficiency was found.

Publication types

  • English Abstract
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Bleomycin / administration & dosage*
  • Bleomycin / therapeutic use
  • Carcinoma, Squamous Cell / therapy*
  • Electric Stimulation Therapy / methods
  • Electrochemistry*
  • Humans
  • Injections, Intravenous
  • Male
  • Middle Aged
  • Mouth Neoplasms / pathology
  • Mouth Neoplasms / therapy*
  • Oropharyngeal Neoplasms / pathology
  • Oropharyngeal Neoplasms / therapy*
  • Skin Neoplasms / secondary

Substances

  • Bleomycin