Inducing motor skill improvements with a declarative task

Nat Neurosci. 2007 Feb;10(2):148-9. doi: 10.1038/nn1836. Epub 2007 Jan 21.


During sequence learning, individuals show motor-skill acquisition and an ability to verbally describe items within the sequence. We disrupted this latter, declarative component by having participants learn a word list immediately after sequence learning. This induced off-line skill improvements. We conclude that off-line memory processing relies not only on the engagement of neuroplastic mechanisms but also on the disengagement of an interaction between declarative and procedural memory systems.

Publication types

  • Research Support, N.I.H., Extramural

MeSH terms

  • Brain / physiology
  • Humans
  • Learning / physiology*
  • Memory / physiology*
  • Motor Skills / physiology*
  • Neuronal Plasticity / physiology*
  • Neuropsychological Tests
  • Verbal Behavior / physiology