Palmitoylation-dependent protein sorting

J Cell Biol. 2007 Jan 29;176(3):249-54. doi: 10.1083/jcb.200610151. Epub 2007 Jan 22.


S-palmitoylation is a posttranslational modification that regulates membrane-protein interactions. However, palmitate is more than just a hydrophobic membrane anchor, as many different types of protein are palmitoylated, including transmembrane proteins. Indeed, there is now compelling evidence that palmitoylation plays a key role in regulating various aspects of protein sorting within the cell.

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Animals
  • Humans
  • Palmitic Acids / metabolism*
  • Protein Processing, Post-Translational / physiology*
  • Protein Transport / physiology*


  • Palmitic Acids