Bleeding gums: duloxetine may be the cause

J Postgrad Med. 2007 Jan-Mar;53(1):44-5. doi: 10.4103/0022-3859.30328.


Duloxetine is a newly introduced drug. It is being prescribed for the management of diabetic neuropathic pain and major depressive disorder. The most frequently observed adverse events with duloxetine are nausea, dry mouth and somnolence, constipation, diarrhea, decreased appetite, weight loss, feeling of fatigue, dizziness, somnolence, hypohidrosis, decreased libido and erectile dysfunction. One of the patients being prescribed the drug developed bleeding gums on being started with the drug which resolved on stopping it. We hereby report this case.

Publication types

  • Case Reports

MeSH terms

  • Adrenergic Uptake Inhibitors / adverse effects*
  • Adult
  • Adverse Drug Reaction Reporting Systems
  • Antidepressive Agents / adverse effects*
  • Depressive Disorder, Major / drug therapy*
  • Dopamine Uptake Inhibitors / adverse effects*
  • Duloxetine Hydrochloride
  • Gingival Hemorrhage / etiology
  • Humans
  • Male
  • Selective Serotonin Reuptake Inhibitors / adverse effects*
  • Thiophenes / adverse effects*


  • Adrenergic Uptake Inhibitors
  • Antidepressive Agents
  • Dopamine Uptake Inhibitors
  • Serotonin Uptake Inhibitors
  • Thiophenes
  • Duloxetine Hydrochloride