Frequency of gamma-Ray Induced Specific Locus and Recessive Lethal Mutations in Mature Germ Cells of the Zebrafish, BRACHYDANIO RERIO

S Chakrabarti; G Streisinger; F Singer; C Walker

doi:10.1093/genetics/103.1.109

Frequency of gamma-Ray Induced Specific Locus and Recessive Lethal Mutations in Mature Germ Cells of the Zebrafish, BRACHYDANIO RERIO

Genetics. 1983 Jan;103(1):109-23. doi: 10.1093/genetics/103.1.109.

Authors

S Chakrabarti¹, G Streisinger, F Singer, C Walker

Affiliation

¹ Institute of Molecular Biology, University of Oregon, Eugene, Oregon 97403.

Abstract

Specific locus and recessive lethal mutations are induced by gamma-rays with approximately first order kinetics in the zebrafish (Brachydanio rerio) with frequencies of 4 x 10(-5) r(-1 ) and 4 x 10(-3) r(-1), respectively. The surprisingly low ratio (100:1) of recessive lethals to specific locus mutations may be due to the induction of large deficiencies by gamma-rays.