Metabolic Syndrome and Cardiometabolic Risk in PCOS

Curr Diab Rep. 2007 Feb;7(1):66-73. doi: 10.1007/s11892-007-0012-8.


The cardiovascular risk associated with the polycystic ovary syndrome (PCOS) has recently attracted much interest. Women with PCOS are more likely to fulfill the diagnosis of the metabolic syndrome, a cluster of related cardiometabolic factors known to predict long-term risk of cardiovascular disease and type 2 diabetes. We review the literature pertaining to the link between the metabolic syndrome, cardiovascular disease, and PCOS. We focus on the influence of obesity and hyperandrogenemia, and on strategies for identifying cardiovascular risk in PCOS.

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Androgens / metabolism
  • Cardiovascular Diseases / complications*
  • Cardiovascular Diseases / metabolism*
  • Cardiovascular Diseases / pathology
  • Disease Progression
  • Female
  • Humans
  • Metabolic Syndrome / complications*
  • Metabolic Syndrome / metabolism*
  • Metabolic Syndrome / pathology
  • Polycystic Ovary Syndrome / complications*
  • Polycystic Ovary Syndrome / metabolism*
  • Polycystic Ovary Syndrome / pathology
  • Risk Factors


  • Androgens