Summing up 100 years of asthma

Zuzana Diamant; J Diderik Boot; J Christian Virchow

doi:10.1016/j.rmed.2006.12.004

Summing up 100 years of asthma

Respir Med. 2007 Mar;101(3):378-88. doi: 10.1016/j.rmed.2006.12.004. Epub 2007 Jan 26.

Authors

Zuzana Diamant¹, J Diderik Boot, J Christian Virchow

Affiliation

¹ Department of Respiratory and Allergy Research, Centre for Human Drug Research, Leiden, Zernikedreef 10, 2333 CL Leiden, The Netherlands. zdiamant@chdr.nl

PMID: 17258900
DOI: 10.1016/j.rmed.2006.12.004

Abstract

In this review, we aim to lead the readers through the historical highlights of pathophysiological concepts and treatment of asthma. Understanding the nature and links of asthma has modeled our diagnostic, pathophysiological and therapeutic thinking and acting. The recognition of its heterogeneous nature in combination with several refined and sophisticated technologies will mark a new era of phenotype-specific approach and treatment of asthma.

Publication types

Historical Article
Review

MeSH terms

Adrenal Cortex Hormones / therapeutic use
Adrenergic beta-Agonists / therapeutic use
Asthma / drug therapy
Asthma / etiology
Asthma / history*
Bronchodilator Agents / therapeutic use
Cholinergic Antagonists / therapeutic use
Histamine H1 Antagonists / therapeutic use
History, 19th Century
History, 20th Century
Humans
Ketotifen / therapeutic use
Leukotriene Antagonists / therapeutic use
Phenotype
Xanthines / therapeutic use

Substances

Adrenal Cortex Hormones
Adrenergic beta-Agonists
Bronchodilator Agents
Cholinergic Antagonists
Histamine H1 Antagonists
Leukotriene Antagonists
Xanthines
Ketotifen