"Recurrent" posterior reversible encephalopathy syndrome: report of 3 cases--PRES can strike twice!

J Comput Assist Tomogr. 2007 Jan-Feb;31(1):148-56. doi: 10.1097/01.rct.0000233127.21303.b9.


In a retrospective review, 3 (3.8%) of 78 patients developed recurrent posterior reversible encephalopathy syndrome. Underlying clinical conditions included sickle cell disease, antibody-positive autoimmune disease, and allogeneic bone marrow transplantation. Infection (bacterial/viral) was suspected or documented in both episodes in all 3 patients. Evidence of endothelial injury (schistocyte formation and increased lactate dehydrogenase) was documented in all patients, and multiple organ dysfunction syndrome developed during the hospital course of all admissions.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Brain Edema / diagnosis*
  • Female
  • Humans
  • Magnetic Resonance Imaging
  • Middle Aged
  • Multiple Organ Failure / diagnosis*
  • Recurrence
  • Retrospective Studies
  • Syndrome
  • Tomography, X-Ray Computed