Case Reports
doi: 10.1056/NEJMoa064725.
Prepubertal gynecomastia linked to lavender and tea tree oils
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- PMID: 17267908
- DOI: 10.1056/NEJMoa064725
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Case Reports
Prepubertal gynecomastia linked to lavender and tea tree oils
N Engl J Med.
.
Free article
Abstract
Most cases of male prepubertal gynecomastia are classified as idiopathic. We investigated possible causes of gynecomastia in three prepubertal boys who were otherwise healthy and had normal serum concentrations of endogenous steroids. In all three boys, gynecomastia coincided with the topical application of products that contained lavender and tea tree oils. Gynecomastia resolved in each patient shortly after the use of products containing these oils was discontinued. Furthermore, studies in human cell lines indicated that the two oils had estrogenic and antiandrogenic activities. We conclude that repeated topical exposure to lavender and tea tree oils probably caused prepubertal gynecomastia in these boys.
2007 Massachusetts Medical Society
Comment in
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Prepubertal gynecomastia linked to lavender and tea tree oils.N Engl J Med. 2007 Jun 14;356(24):2541-2; author reply 2543-4. doi: 10.1056/NEJMc070572. N Engl J Med. 2007. PMID: 17568039 No abstract available.
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Prepubertal gynecomastia linked to lavender and tea tree oils.N Engl J Med. 2007 Jun 14;356(24):2543; author reply 2543-4. N Engl J Med. 2007. PMID: 17575591 No abstract available.
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Prepubertal gynecomastia linked to lavender and tea tree oils.N Engl J Med. 2007 Jun 14;356(24):2542; author reply 2543-4. N Engl J Med. 2007. PMID: 17575592 No abstract available.
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Prepubertal gynecomastia linked to lavender and tea tree oils.N Engl J Med. 2007 Jun 14;356(24):2542-3; author reply 2543-4. N Engl J Med. 2007. PMID: 17575593 No abstract available.
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Lack of evidence that essential oils affect puberty.Reprod Toxicol. 2014 Apr;44:50-1. doi: 10.1016/j.reprotox.2013.09.010. Epub 2014 Feb 17. Reprod Toxicol. 2014. PMID: 24556344 No abstract available.
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