Abstract
In 1905 the Cambridge physiologist Keith Lucas extended the "all-or-none" principle (introduced by H. P. Bowditch for the cardiac tissue) to skeletal muscle and nerve fibres. Nevertheless, in a short time it was clear that nerve fibres obey this law, but also that frequency of discharge is another relevant factor in the nervous conduction.
MeSH terms
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Animals
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Germany
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History, 19th Century
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History, 20th Century
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Humans
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Models, Animal
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Motor Neurons / physiology*
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Muscle Contraction / physiology
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Muscle, Skeletal / innervation*
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Muscle, Skeletal / physiology*
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Neural Conduction / physiology
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Neuromuscular Junction / physiology
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Neurophysiology / history*
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Peripheral Nerves / physiology*
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United Kingdom