A possible effect of testosterone on the adenosine 3'-5' cyclic monophosphate levels in rat cerebral cortex. A brief note

I D Zimmerman; K Isaacs

doi:10.1016/0047-6374(75)90023-8

A possible effect of testosterone on the adenosine 3'-5' cyclic monophosphate levels in rat cerebral cortex. A brief note

Mech Ageing Dev. 1975 May-Aug;4(3-4):215-9. doi: 10.1016/0047-6374(75)90023-8.

Authors

I D Zimmerman, K Isaacs

PMID: 172745
DOI: 10.1016/0047-6374(75)90023-8

Abstract

Based on a correlation of serum testosterone levels and cortical cyclic-AMP concentrations in a normal aging population of male CD Fischer rats and a demonstration of decreased cortical cyclic-AMP subsequent to injection of testosterone, it was concluded that a cause and effect relation between hormone concentrations and brain cyclic nucleotide levels is tenable.

Publication types

Research Support, U.S. Gov't, P.H.S.

MeSH terms

Aging
Animals
Brain Chemistry* / drug effects
Cerebral Cortex / metabolism*
Cyclic AMP / metabolism*
Male
Rats
Testosterone / blood
Testosterone / pharmacology*
Testosterone / physiology

Substances

Testosterone
Cyclic AMP