Does repeated disinfection of the e-Flow rapid nebulizer affect in vitro performance?

J Cyst Fibros. 2007 Jul;6(4):309-10. doi: 10.1016/j.jcf.2006.12.008. Epub 2007 Feb 2.


Repeated disinfection of a nebulizer may modify its performance. During 60 cycles of disinfection with the Nuk steam sterilizer (120 nebulizations), the median volume diameter of tobramycin or colistin, nebulization time and various parameters correlated with the membrane weight of the e-Flow rapid are not modified. Results are similar when tap or purified water is used for washing and disinfection.

MeSH terms

  • Administration, Inhalation
  • Anti-Bacterial Agents / administration & dosage*
  • Cross Infection / prevention & control
  • Cystic Fibrosis / drug therapy*
  • Disinfection / methods*
  • Humans
  • In Vitro Techniques
  • Nebulizers and Vaporizers / microbiology*
  • Reproducibility of Results


  • Anti-Bacterial Agents