DFprot: a webtool for predicting local chain deformability

Bioinformatics. 2007 Apr 1;23(7):901-2. doi: 10.1093/bioinformatics/btm014. Epub 2007 Feb 3.


DFprot is a web-based server for predicting main-chain deformability from a single protein conformation. The server automatically performs a normal-mode analysis (NMA) of the uploaded structure and calculates its capability to deform at each of its residues. Non-specialists can easily and rapidly obtain a quantitative first approximation of the flexibility of their structures with a simple and efficient interface.

Availability: http://sbg.cib.csic.es/Software/DFprot.

Publication types

  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Algorithms
  • Amino Acid Sequence
  • Computer Simulation
  • Elasticity
  • Internet*
  • Models, Chemical*
  • Models, Molecular*
  • Molecular Sequence Data
  • Protein Conformation
  • Protein Structure, Tertiary
  • Proteins / chemistry*
  • Proteins / ultrastructure*
  • Sequence Alignment / methods
  • Sequence Analysis, Protein / methods*
  • Software*


  • Proteins