A provocative test to determine brain compliance in the management of patients with hydrocephalus

Conf Proc IEEE Eng Med Biol Soc. 2005:2005:6687-90. doi: 10.1109/IEMBS.2005.1616037.

Abstract

Non-invasive techniques to explore intracranial compliance and pressure have been extensively explored in recent years. Previous techniques have used expensive technologies to make these measurements, often with difficulty. We present a novel, inexpensive method and algorithm to observe trends in intracranial compliance measurement targeted towards the treatment and management of hydrocephalus. The technique uses two photo-plethysmographic sensors to record arterial pulse perfusion, a common tilt table apparatus to methodically and artificially increase intracranial pressure, and a digital signal processing algorithm to determine phase difference between the waveforms. A secondary phase-difference disease signature approach is also hypothesized.