Time trends in reported diagnoses of childhood neuropsychiatric disorders: a Danish cohort study

Arch Pediatr Adolesc Med. 2007 Feb;161(2):193-8. doi: 10.1001/archpedi.161.2.193.


Objectives: To examine trends in autism (autism spectrum disorder and childhood autism) in the context of 3 additional childhood neuropsychiatric disorders: hyperkinetic disorder, Tourette syndrome, and obsessive-compulsive disorder.

Design: Population-based cohort study.

Setting: Children were identified in the Danish Medical Birth Registry. Relevant outcomes were obtained via linkage with the Danish National Psychiatric Register, which included reported diagnoses through 2004 by psychiatrists using diagnostic criteria from the International Statistical Classification of Diseases, 10th Revision.

Participants: All children born in Denmark from 1990 through 1999, a total of 669 995 children.

Main outcome measures: Cumulative incidence proportion by age, stratified by year of birth, for each disorder.

Results: Statistically significant increases were found in cumulative incidence across specific birth years for autism spectrum disorder, childhood autism, hyperkinetic disorder, and Tourette syndrome. No significant change in cumulative incidence was observed for obsessive-compulsive disorder.

Conclusions: Recent increases in reported autism diagnoses might not be unique among childhood neuropsychiatric disorders and might be part of a more widespread epidemiologic phenomenon. The reasons for the observed common pattern of change in reported cumulative incidence could not be determined in this study, but the data underscore the growing awareness of and demand for services for children with neurodevelopmental disorders in general.

MeSH terms

  • Autistic Disorder / diagnosis
  • Autistic Disorder / epidemiology*
  • Child
  • Child Health Services / organization & administration
  • Child Welfare / trends*
  • Child, Preschool
  • Cohort Studies
  • Denmark / epidemiology
  • Female
  • Humans
  • Incidence
  • Infant
  • Infant, Newborn
  • Male
  • Mass Screening / statistics & numerical data
  • Motor Skills Disorders / diagnosis
  • Motor Skills Disorders / epidemiology*
  • Obsessive-Compulsive Disorder / diagnosis
  • Obsessive-Compulsive Disorder / epidemiology*
  • Tourette Syndrome / diagnosis
  • Tourette Syndrome / epidemiology*