Parental attitudes to pre-pubertal HPV vaccination

Vaccine. 2007 Mar 1;25(11):1945-52. doi: 10.1016/j.vaccine.2007.01.059. Epub 2007 Jan 22.


Objectives: To determine the acceptability of childhood HPV vaccination and examine demographic, cultural, and psychosocial predictors of vaccine acceptance.

Design: School-based survey.

Participants: Questionnaires sent to 1205 mothers of 8-14-year-old girls. Responses from 684 were included in the analyses.

Setting: Ten schools (seven primary, three secondary) in four areas of England.

Results: Seventy-five percent of mothers would accept the vaccine for their daughter. Vaccine acceptance was higher in mothers who had experience of cancer in the family (OR=1.61, CI: 1.14-2.29), had older daughters (OR=1.15, CI: 1.04-1.27), perceived approval from husband/partner (OR=14.51, CI: 6.15-34.25) and believed vaccine acceptance would be more normative (OR=1.78, CI: 1.59-2.01). Having concerns about too many vaccinations (OR=0.22, CI: 0.15-0.31) or vaccine side effects (OR=0.37, CI: 0.28-0.50) and worry about increasing promiscuity (OR=0.47, CI: 0.36-0.62) emerged as deterrents. The modal preferred age was 12 years. Endorsing vaccination at earlier ages was predicted by feeling able to discuss related topics, including sex, at younger ages (OR=1.37, CI: 1.24-1.51) and concern about increasing promiscuity (OR=0.61, CI: 0.47-0.78).

Conclusions: Overall, there was a favourable response to HPV vaccination. Emphasising the widespread acceptance of the vaccine might promote acceptance further, as would information on immunological and social benefits of earlier vaccination.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adolescent
  • Adult
  • Attitude to Health*
  • Child
  • Data Collection
  • England
  • Female
  • Humans
  • Mothers / psychology*
  • Papillomavirus Vaccines*
  • Parents / psychology*
  • Surveys and Questionnaires
  • Vaccination / psychology*


  • Papillomavirus Vaccines