Abstract
Fetal exposure to angiotensin-converting enzyme inhibitors (ACEIs) is associated with increased neonatal morbidity and mortality. Long-term follow-up of three patients with fetal ACEI exposure revealed impaired renal function in two, severe hypertension and proteinuria in one and isolated polycythaemia in all three. Careful long-term follow-up of children with ACEI fetopathy is recommended.
MeSH terms
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Adolescent
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Angiotensin-Converting Enzyme Inhibitors / adverse effects*
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Child
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Enalapril / adverse effects*
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Female
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Fetus / drug effects*
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Humans
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Hypertension / chemically induced
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Kidney Diseases / chemically induced
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Male
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Polycythemia / chemically induced
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Pregnancy
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Prenatal Exposure Delayed Effects*
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Proteinuria / chemically induced
Substances
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Angiotensin-Converting Enzyme Inhibitors
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Enalapril