Angiotensin-converting enzyme inhibitor fetopathy: long-term outcome

Arch Dis Child Fetal Neonatal Ed. 2007 Sep;92(5):F402-3. doi: 10.1136/adc.2006.101717. Epub 2007 Feb 6.

Abstract

Fetal exposure to angiotensin-converting enzyme inhibitors (ACEIs) is associated with increased neonatal morbidity and mortality. Long-term follow-up of three patients with fetal ACEI exposure revealed impaired renal function in two, severe hypertension and proteinuria in one and isolated polycythaemia in all three. Careful long-term follow-up of children with ACEI fetopathy is recommended.

Publication types

  • Case Reports

MeSH terms

  • Adolescent
  • Angiotensin-Converting Enzyme Inhibitors / adverse effects*
  • Child
  • Enalapril / adverse effects*
  • Female
  • Fetus / drug effects*
  • Humans
  • Hypertension / chemically induced
  • Kidney Diseases / chemically induced
  • Male
  • Polycythemia / chemically induced
  • Pregnancy
  • Prenatal Exposure Delayed Effects*
  • Proteinuria / chemically induced

Substances

  • Angiotensin-Converting Enzyme Inhibitors
  • Enalapril