[Lynch syndrome and gynaecologic's cancer: follow-up recommendations]

K Magri; G Millon

doi:10.1016/j.jgyn.2006.09.005

[Lynch syndrome and gynaecologic's cancer: follow-up recommendations]

J Gynecol Obstet Biol Reprod (Paris). 2007 Feb;36(1):68-71. doi: 10.1016/j.jgyn.2006.09.005. Epub 2007 Jan 9.

[Article in French]

Authors

K Magri¹, G Millon

Affiliation

¹ Service de Chirurgie Générale, Viscérale et Vasculaire, CHG de Lons-le-Saunier, 55, rue du Docteur-Jean-Michel, BP 364, 39016 Lons-le-Saunier cedex, France. keith.magri@wanadoo.fr

PMID: 17293255
DOI: 10.1016/j.jgyn.2006.09.005

Abstract

The Lynch syndrome or HNPCC, is due to a mutation of the genes pertaining to the system MMR. This frequency varies from 1/1000 to 1/400. It's responsible for 6% of endométrial cancers, 2% of ovarian cancers and 1 to 3% of colorectal cancers. A good knowledge of this syndrome is necessary for doing the diagnosis and adjustment of gynaecological and colorectal follow-up. The authors report four cases in Lynch syndrome family.

Publication types

Case Reports
English Abstract

MeSH terms

Aged
Colorectal Neoplasms, Hereditary Nonpolyposis* / complications
Colorectal Neoplasms, Hereditary Nonpolyposis* / diagnosis
Colorectal Neoplasms, Hereditary Nonpolyposis* / genetics
Endometrial Neoplasms / diagnosis
Endometrial Neoplasms / epidemiology
Endometrial Neoplasms / genetics*
Female
Genetic Predisposition to Disease
Humans
Male
Middle Aged
Ovarian Neoplasms / diagnosis
Ovarian Neoplasms / epidemiology
Ovarian Neoplasms / genetics*
Pedigree
Risk Factors