Carbamazepine poisoning managed with haemodialysis and haemoperfusion in three adolescents

Nephrology (Carlton). 2007 Feb;12(1):33-5. doi: 10.1111/j.1440-1797.2006.00663.x.

Abstract

Carbamazepine is a widely used antiepileptic agent. Accidental or suicidal overdose in children is not uncommon. Acute toxicity is associated with seizures, coma, arrhythmias and death in severe cases. Here we report three adolescents with carbamzepine overdose, two managed with standard low-flux haemodialysis and one with charcoal haemoperfusion. Our report emphasizes that haemodialysis might be a cheaper and easier alternative for carbamazepine overdose in milder cases, with fewer side-effects than haemoperfusion.

Publication types

  • Case Reports

MeSH terms

  • Adolescent
  • Anticonvulsants / poisoning*
  • Carbamazepine / poisoning*
  • Charcoal / administration & dosage*
  • Child
  • Drug Overdose / physiopathology
  • Drug Overdose / therapy*
  • Female
  • Hemoperfusion*
  • Humans
  • Length of Stay
  • Male
  • Renal Dialysis*
  • Treatment Outcome

Substances

  • Anticonvulsants
  • Charcoal
  • Carbamazepine