Vitamin E and neurodegenerative diseases

Mol Aspects Med. Oct-Dec 2007;28(5-6):591-606. doi: 10.1016/j.mam.2007.01.004. Epub 2007 Jan 11.


Vitamin E is essential for neurological function. This fact, together with a growing body of evidence indicating that neurodegenerative processes are associated with oxidative stress, lead to the convincing idea that several neurological disorders may be prevented and/or cured by the antioxidant properties of vitamin E. In this review, some aspects related to the role of vitamin E against Alzheimer's disease, Parkinson's disease, amyotrophic lateral sclerosis and ataxia with vitamin E deficiency will be presented.

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Alzheimer Disease / metabolism
  • Alzheimer Disease / prevention & control
  • Amyotrophic Lateral Sclerosis / metabolism
  • Amyotrophic Lateral Sclerosis / prevention & control
  • Animals
  • Humans
  • Neurodegenerative Diseases / metabolism*
  • Neurodegenerative Diseases / prevention & control*
  • Parkinson Disease / metabolism
  • Parkinson Disease / prevention & control
  • Vitamin E / metabolism*
  • Vitamin E / pharmacology*
  • Vitamin E Deficiency / metabolism
  • Vitamin E Deficiency / prevention & control


  • Vitamin E