Skip to main page content
Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Randomized Controlled Trial
. 2007 Mar;31(3):470-8.
doi: 10.1007/s00268-006-0600-9.

Pneumatic Dilatation or Laparoscopic Cardiomyotomy in the Management of Newly Diagnosed Idiopathic Achalasia. Results of a Randomized Controlled Trial

Affiliations
Randomized Controlled Trial

Pneumatic Dilatation or Laparoscopic Cardiomyotomy in the Management of Newly Diagnosed Idiopathic Achalasia. Results of a Randomized Controlled Trial

S Kostic et al. World J Surg. .

Abstract

Background: The most effective therapeutic strategy in newly diagnosed achalasia is yet to be established. Therefore we designed a study in which pneumatic dilatation was compared to laparoscopic cardiomyotomy to which was added a partial posterior fundoplication.

Patients and results: A series of 51 patients (24 males, mean age 44 years) were randomly allocated to the therapeutic modalities (dilatation = 26, surgery = 25). All patients were followed for at least 12 months, and during that period the pneumatic dilatations strategy had significantly more treatment failures (P = 0.04). Only minor differences emerged between the study groups when symptoms, dysphagia scorings, and quality-of-life assessments were evaluated 12 months after initiation of therapy.

Conclusions: Laparoscopic myotomy was found to be superior to an endoscopic balloon dilatation strategy in the treatment of achalasia when studied during the first 12 months after treatment.

Similar articles

See all similar articles

Cited by 38 articles

See all "Cited by" articles

References

    1. Scand J Gastroenterol Suppl. 1993;199:18-21 - PubMed
    1. Gastroenterology. 1986 Apr;90(4):978-83 - PubMed
    1. Surg Endosc. 2004 Apr;18(4):691-5 - PubMed
    1. Scand J Gastroenterol Suppl. 1996;221:8-13 - PubMed
    1. Gut. 1992 Aug;33(8):1011-5 - PubMed

Publication types

LinkOut - more resources

Feedback