Circulating tumour-derived nucleic acids in cancer patients: potential applications as tumour markers

Br J Cancer. 2007 Mar 12;96(5):681-5. doi: 10.1038/sj.bjc.6603625. Epub 2007 Feb 20.


Tumour-associated changes have been observed in the circulating nucleic acids of cancer patients and have been proposed to be useful for the detection and monitoring of cancers. In this review, different approaches for detecting tumour-associated nucleic acids in the circulation and their potential applications as tumour markers are discussed.

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Biomarkers, Tumor / blood*
  • DNA, Neoplasm / blood*
  • Humans
  • Neoplasms / blood*
  • Neoplasms / diagnosis*
  • Neoplasms / genetics
  • Nucleic Acids / blood*


  • Biomarkers, Tumor
  • DNA, Neoplasm
  • Nucleic Acids