Formal synthesis of (+)-SCH 351448: the Prins cyclization approach

Chem Commun (Camb). 2007 Mar 7:(9):939-41. doi: 10.1039/b616558c. Epub 2007 Jan 24.

Abstract

The formal synthesis of (+)-SCH 351448 has been accomplished with the catalytic Prins cyclization strategy, yielding the monomeric unit as a single isomer.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Cyclization
  • Lactones / chemical synthesis*
  • Lactones / chemistry
  • Receptors, LDL / agonists

Substances

  • Lactones
  • Receptors, LDL
  • SCH 351448