20S proteasome and its inhibitors: crystallographic knowledge for drug development

Chem Rev. 2007 Mar;107(3):687-717. doi: 10.1021/cr0502504. Epub 2007 Feb 23.
No abstract available

Publication types

  • Review

MeSH terms

  • Amino Acid Sequence
  • Animals
  • Binding Sites
  • Crystallography, X-Ray
  • Drug Design*
  • Enzyme Inhibitors* / chemistry
  • Enzyme Inhibitors* / pharmacology
  • Humans
  • Molecular Sequence Data
  • Proteasome Endopeptidase Complex / chemistry
  • Proteasome Inhibitors*
  • Sequence Alignment
  • Structure-Activity Relationship
  • Substrate Specificity

Substances

  • Enzyme Inhibitors
  • Proteasome Inhibitors
  • Proteasome Endopeptidase Complex