Modern management of vestibular schwannomas

Prog Neurol Surg. 2007:20:129-141. doi: 10.1159/000100100.


Within the last 3 decades, microsurgery and stereotactic radiosurgery (SRS) have become well-established management options for vestibular schwannomas (VSs). Advancement in the management of VSs can be separated into three periods: the microsurgical pioneer period, the demonstration of SRS as a first-line therapy for small and medium-sized VSs, and currently, a period of SRS maturity based on a large worldwide patient accrual. The Marseille SRS experience includes 1,500 patients, with 1,000 patients having follow-up longer than 3 years. A long-term tumor control rate of 97%, transient facial palsy lower than 1%, and a probability of functional hearing preservation between 50 and 95% was achieved in this large series of patients treated with state-of-the-art SRS.

MeSH terms

  • Facial Paralysis / etiology
  • Facial Paralysis / prevention & control
  • Humans
  • Hydrocephalus / etiology
  • Microsurgery
  • Nervous System Diseases / etiology
  • Neurofibromatosis 2 / etiology
  • Neuroma, Acoustic / pathology
  • Neuroma, Acoustic / surgery*
  • Postoperative Complications / epidemiology*
  • Radiosurgery* / adverse effects
  • Treatment Outcome
  • Vestibule, Labyrinth / radiation effects